
J2-1731
Acronym: C-MAP
Institution: Faculty of Electrical engineering and Computer science, University of Maribor
Project type: Basic research project (national)
Implementation period: 1.7.2019―30.6.2022
Budget: 300.000,00 €
Project website: https://lspo.feri.um.si/CMAP/index-en.php
PROJECT SUMMARY:
Compound muscle action potential (CMAP) is the sum of motor unit action potentials (MUAPs) in the muscle, elicited by electrical or mechanical stimulation of nerves and muscles or by transcranial magnetic (TMS) or electric stimulation (TES) of the motor cortex. CMAP analysis is routinely applied in clinical and neurophysiologic studies to non-invasively assess the functional status of a human motor system in vivo, to evaluate motor tract integrity and quantify responses of neuromuscular circuits to training, rehabilitation and degeneration due to various neuromuscular disorders, to study corticospinal excitability, to assess motor nerve conduction properties, fatigue and biomechanical responses in skeletal muscles. In submaximal stimulations, elicited CMAPs are highly variable. This problem of submaximal CMAP variability has not yet been systematically addressed, mainly due to the lack of CMAP decomposition techniques. In the project, we are developing new computer-aided and fully automated techniques for EMG-based CMAP decomposition to contributions of different motor units and mutually comparing the individual motor unit behaviour in stimulated and voluntary contractions.

Project Coordinator:
Name and surname: Aleš Holobar
Email: ales.holobar@um.si
Personal Profile: LSPO – Aleš Holobar